How Palmitoyle-Thanolamide (PEA) Helps with Pain Relief

Pain is one factor that we cannot escape from. They say that if you take your mind off it and try to distract yourself with something else, you will find relief but this works only temporarily. There are thousands of pain relief meds in the market that target pain. Popping pills is not the right answer but taking the right one definitely is.

The Key to Pain Relief

Today, we are going to talk about Palmitoyle-Thanolamide (PEA), which is fatty acid amide. In medical terms, this fatty acid amide minds to a receptor targeting the cell nucleus and exerts various biological functions that help with inflammation, acute pain and chronic pain.

Understanding Palmitoyle-Thanolamide (PEA)

In simpler terms, PEA is produced in your body and combats pain. One factor it is known for is that it safely boosts natural cannabinoids, which help maintain balance in the body. It protects nerves in the entire body and benefits patients who deal with pain on a daily basis due to disorders that are difficult to treat.

NCBI reports around 10 studies that were done to find out the efficacy of PEA. Data from 786 patients was reviewed and it was found out that PEA responds to different types of pains in different manners. A conclusion was reached that the supplement is useful in treating pain.

Since cannabinoids and PEA help with nerve communication, patients find relief from pain in a safe and a natural way. PEA is naturally found in egg yolks, soy lecithin, soybeans, peanuts, and alfalfa. It is also available in powder, capsule and tablet supplement form. Since PEA’s discovery in 1950, researchers have considered a natural and safe pain killer. According to a study published in the British Journal of Clinical Pharmacology, PEA showed no signs of side effects when it was tested for a period of 60 days. However, further studies need to be done for longer period of times to find its long term effects.

During these studies, it was revealed that PEA and the cannabinoid receptors provide many more benefits than just pain relief, which include reducing allergies, protecting the heat and brain, improving mood and fighting against common cold.

Mechanism of Action

Palmitoyle-Thanolamide activates the anti-inflammatory, energy-boosting and fat-burning PRAR alpha. This is a key protein that stops pro-inflammatory genes from becoming active. A bliss gene by the name FAAH is a stopped from becoming active, which increases the calming effects of anandamide in the body and helps increase relaxation by combating pain.

PEA helps find relief from the following pain types:

  • Pelvic pain due to endometriosis
  • Fibromyalgia
  • Sciatica
  • Peripheral neuropathy
  • Carpal tunnel syndrome
  • Back surgery pain
  • Arthritis pain
  • Cancer pain

Even though PEA is a natural pain killer and so far hasn’t revealed any side effects in its clinical trials, people should only use it after getting it recommended by a doctor.

Digestive Enzymes: What They Are, What They Do, and How They Affect Stomach Health

Do you often experience abdominal pain or other stomach-related problems such as constipation, diarrhea, reflux (heartburn) and so on? Have you gained excessive weight and/ or have difficulty losing weight despite keeping a strict check on your diet? Or worse still, are you losing weight without making any conscious efforts on your behalf?

If even one of the above conditions seems to fit your case, then beware! It might be indicative of a problem with your digestive system.

Most people treat such stomach issues very lightly until they become too severe to be ignored. Unfortunately, at least 1 in every 5 American suffers from Irritable Bowel Syndrome (IBS) and most of them are unaware of how it can be treated. Based on diagnosis, doctors normally suggest lifestyle changes (exercising, healthy eating, reducing stress etc) as the most non-invasive form of treatment. Despite this, many patients doubt the effectiveness of these changes and prefer going on heavy medications instead.  This is usually because they are oblivious of digestive enzymes present naturally in the body and the beneficial effects that they have on stomach health.

Digestive Enzymes and their Purpose in the Human Body

You might already know that enzymes are biological catalysts that support various functions in our body. Digestive enzymes are those that specifically aid digestion and therefore, support gut health.

Various organs in our body produce digestive enzymes including the pancreas, liver, small intestine, and stomach as well as the salivary glands located underneath the tongue. The main purpose of these enzymes is to break down the large food molecules into much smaller ones so that they can be easily absorbed into the bloodstream and transported to the required cells within the body.

Types of Digestive Enzymes

Digestive enzymes are of different types – each type helps break down different food molecules to deliver the nutrients to the body. The three main classes are as follows.

  1. Proteolytic Enzymes – needed to digest protein
  2. Amylases – required to break down carbohydrates
  3. Lipases – needed to break down large fat molecules

Proteolytic enzymes like pepsin are found in gastric juices and produce polypeptides from protein molecules. Amylases are found in the saliva and pancreatic juices and their primary aim is to break down large starch molecules into a smaller compound called maltose. Similarly, lipases are produced in the pancreas and helps in digesting fatty acids.

Together, these digestive enzymes turn the complex food particles into useful substances like amino acids, glucose, nucleic acids, good cholesterol, and fatty acids that are either stored up by the body or use in other biological reactions to keep the organs healthy and strong.

Digestive Enzymes and Stomach Health

By enabling complete and proper breakdown of the food we eat, digestive enzymes do not just alleviate stomach discomfort and prevent constipation, but also improve nutrient absorption and prevent deficiencies. Although further research is still needed to say this for sure, but clinical trials show promising results for the use of supplemental digestive enzymes in  treating IBS.

Nicotinamide Riboside to Help Slow Aging – What It Is, How It Works, and Potential Benefits

Everyone wants healthy and glowing skin – skin that is free of wrinkles and radiates beauty from deep within. Every year, the cosmetic industry earns billions of dollars just from the sale of skin care products alone. This is because when it comes to looking young, most people don’t hesitate to spend on anti-aging products regardless of how much they may cost.

Whether you are looking for the best anti-aging solutions or are someone who’s involved in the cosmetic industry in any other way, it goes without saying that you must be aware of the buzz created by nicotinamide riboside in today’s market.

Are you wondering what the hype is all about? If you are looking for the answer to questions such as what nicotinamide riboside is, how it works, what are its benefits and so on, then keep reading to find out.

What is Nicotinamide Riboside?

Nicotinamide riboside (NR), sometimes also referred to as niagen, is basically a type of vitamin B3 that was discovered quite a few years ago. It was found in trace amounts in milk but wasn’t given much importance until recently when studies suggested that this compound can help slow down aging.

What contributes to its high popularity is the fact that while most anti-aging products normally try improving skin elasticity or use similar techniques to reduce wrinkles from the outside, nicotinamide riboside targets your skin cells from the inside. In other words, NR aims to reverse the entire aging process in the real sense.

Nicotinamide Riboside and Skin Aging – How Does it Work?

Nicotinamide adenine dinucleotide (NAD+) is a substance that is naturally present in our bodies since birth. The amount of NAD+ gradually decreases with the passage of time and is one of the main reasons why skin gets wrinkled as we grow older.

Low NAD+ levels are also a leading cause of other old age problems such as heart disease, diabetes, Alzheimer’s, and loss of vision.  

NR works by converting in the coenzyme, NAR+ upon entering your body. Supplements containing nicotinamide riboside help raise the NAR+ level which further helps speed up key biological processes. For instance, NR-based supplements can repair damaged DNA, boost immunity, set the circadian rhythm and improve muscle strength and quality which in turn help you stay active in addition to giving you naturally glowing and wrinkle-free skin.

Benefits of Nicotinamide Riboside

Potential skin-related health benefits of supplements rich in NR include the following.

Easily Converted Into NAD+

Compared to other types of vitamins, NR is not only converted into NAD+ easily but also accepted readily by the body. Appropriate intake of NR raised the blood NAD+ by almost three times in animal trials.

Supports Healthy Aging

By raising the NAR+ level, nicotinamide riboside activates enzymes like sirtuins. These biological molecules are known to reduce skin inflammation, strengthen DNA, and also enhance mood by making you more stress-resistant.

In other words, nicotinamide riboside can slow down aging by lessening its harmful effects and supporting an overall healthy aging process. However, it must be noted that the effectiveness of nicotinamide for slow aging is not yet well-established because NR-supplements have mainly been tested only on animals so far.

Further clinical trials are yet to be performed to determine the benefits it offers to humans.

What Every Man Needs to Know About Prostate Health

According to research, one in every nine men in the U.S is diagnosed with prostate cancer at some point during his life. Approximately 8 out of 10 males in America develop an enlarged prostate, whereas 90% of all men suffer from a condition called Benign Prostatic Hyperplasia (BPH) once they cross the age of 85. [Source:]

A major reason why these statistics are so alarmingly high is a lack of awareness about prostate health. As a matter of fact, most men aren’t even aware of what this organ does and therefore, don’t realize that they might have a problem until it becomes too severe to be ignored.

Having proper information plays a vital role in dealing with this aspect of men’s health. Take a look at the following article to learn the essentials of prostate health that every man ought to know.  

Enlarged Gland and Prostate Cancer

Prostate cancer is treatable if detected in its early stages. The most common sign of prostate cancer is an excessively increased urge to urinate frequently, especially during the night. Not only does it become difficult to control and pass urine, but you might also experience pain when doing so. If you notice blood when urinating, contact your doctor as soon as possible. Other signs of prostate cancer in the more advanced stages include severe pain in the pelvis, spine, legs, or even ribs.   

Problems in urinating can also signify an enlarged prostate gland because the symptoms of enlarged prostate overlap with those of prostate cancer in its initial stages. Get your PSA blood level checked and consult doctors for further screening, if required.

Tips for Prostate Health

There has been quite a debate about whether eating habits and lifestyle are linked with prostate cancer or not. However, there’s no denying that taking a proper diet and exercising regularly help you stay healthy and can delay – if not completely eliminate – your chances of having a prostate problem.

Change Your Eating Habits

Researchers believe that eating a nutritious diet that comprises of more fresh fruits and vegetables protect the prostate. Specific food items that must be incorporated in your diet include the following.

  • Citrus fruits such as oranges, lemons, grapefruits, and limes
  • Green vegetables like broccoli, cabbage, and bok choy contain a chemical called sulforaphane that targets cancer cells and can help prevent prostate cancer
  • Nuts such as walnuts, pecans, and almonds. These are rich in zinc which balances testosterone levels and promotes prostate health.

On the other hand, you must avoid the following food items that can lead to an enlarged prostate.

  • Red meat
  • Excessive consumption of dairy products including butter, cheese, and milk
  • Caffeinated drinks like tea, coffee and especially sodas. Caffeine acts as a diuretic which means it directly affect your urinary system and can affect prostate health.

Health comes first. If you notice any of the symptoms discussed above or feel that there might be something wrong with your prostate, don’t hesitate or delay consulting an expert physician.